Prognostic significance of RNA-based TP53 pathway function among estrogen receptor positive and negative breast cancer cases

Prognostic significance of RNA-based TP53 pathway function among estrogen receptor positive and negative breast cancer cases

Abstract TP53 and estrogen receptor (ER) are essential in breast cancer development and progression, but TP53 status (by DNA sequencing or protein expression) has been inconsistently associated with survival. We evaluated whether RNA-based TP53 classifiers are related to survival. Participants inclu...

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Bibliographic Details
Main Authors: Amber N. Hurson, Mustapha Abubakar, Alina M. Hamilton, Kathleen Conway, Katherine A. Hoadley, Michael I. Love, Andrew F. Olshan, Charles M. Perou, Montserrat Garcia-Closas, Melissa A. Troester
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-022-00437-7

Internet

https://doi.org/10.1038/s41523-022-00437-7

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