Screening of a Novel Peptide Targeting the Proteoglycan-Like Region of Human Carbonic Anhydrase IX

The extracellular domain of human carbonic anhydrase IX (CA IX) is extended by a proteoglycan-like region (PGLR). The aim of the present study was the development of novel molecules with specificity for PGLR, which may be used for tumor targeting and imaging. PGLR was chemically synthesized, and pha...

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Bibliographic Details
Main Authors: Shoaib Rana, Felix Nissen, Thomas Lindner, Annette Altmann, Walter Mier, Juergen Debus, Uwe Haberkorn, Vasileios Askoxylakis
Format: Article
Language:English
Published: SAGE Publications 2013-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2013.00066