Interleukin-1β Promotes Ovarian Tumorigenesis through a p53/NF-κB-Mediated Inflammatory Response in Stromal Fibroblasts

Cancer has long been considered a disease that mimics an “unhealed wound,” with oncogene-induced secretory activation signals from epithelial cancer cells facilitating stromal fibroblast, endothelial, and inflammatory cell participation in tumor progression. However, the underlying mechanisms that o...

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Bibliographic Details
Main Authors: Isaiah Gregory Schauer, Jing Zhang, Zhen Xing, Xiaoqing Guo, Imelda Mercado-Uribe, Anil K. Sood, Peng Huang, Jinsong Liu
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800486