Periaqueductal grey and spinal cord pathology contribute to pain in Parkinson’s disease

Abstract Pain is a key non-motor feature of Parkinson’s disease (PD) that significantly impacts on life quality. The mechanisms underlying chronic pain in PD are poorly understood, hence the lack of effective treatments. Using the 6-hydroxydopamine (6-OHDA) lesioned rat model of PD, we identified re...

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Bibliographic Details
Main Authors: Yazead Buhidma, Carl Hobbs, Marzia Malcangio, Susan Duty
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00510-3