Periaqueductal grey and spinal cord pathology contribute to pain in Parkinson’s disease
Abstract Pain is a key non-motor feature of Parkinson’s disease (PD) that significantly impacts on life quality. The mechanisms underlying chronic pain in PD are poorly understood, hence the lack of effective treatments. Using the 6-hydroxydopamine (6-OHDA) lesioned rat model of PD, we identified re...
Main Authors: | Yazead Buhidma, Carl Hobbs, Marzia Malcangio, Susan Duty |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-023-00510-3 |
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