Bacillus anthracis secretes proteins that mediate heme acquisition from hemoglobin.

Acquisition of iron is necessary for the replication of nearly all bacterial pathogens; however, iron of vertebrate hosts is mostly sequestered by heme and bound to hemoglobin within red blood cells. In Bacillus anthracis, the spore-forming agent of anthrax, the mechanisms of iron scavenging from he...

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Bibliographic Details
Main Authors: Anthony W Maresso, Gabriella Garufi, Olaf Schneewind
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2515342?pdf=render