Bacillus anthracis secretes proteins that mediate heme acquisition from hemoglobin.
Acquisition of iron is necessary for the replication of nearly all bacterial pathogens; however, iron of vertebrate hosts is mostly sequestered by heme and bound to hemoglobin within red blood cells. In Bacillus anthracis, the spore-forming agent of anthrax, the mechanisms of iron scavenging from he...
Main Authors: | Anthony W Maresso, Gabriella Garufi, Olaf Schneewind |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-08-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2515342?pdf=render |
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