A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation

A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation

Metastasis is a multistep process in which cells must detach, migrate/invade local structures, intravasate, circulate, extravasate, and colonize. A full understanding of the complexity of this process has been limited by the lack of ability to study these steps in isolation with detailed molecular a...

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Bibliographic Details
Main Authors: Tyler A. Allen, Mark M. Cullen, Nathan Hawkey, Hiroyuki Mochizuki, Lan Nguyen, Elyse Schechter, Luke Borst, Jeffrey A. Yoder, Jennifer A. Freedman, Steven R. Patierno, Ke Cheng, William C. Eward, Jason A. Somarelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
angiopellosis
circulating tumor cell cluster
tumor cell extravasation
cancer exodus hypothesis
metastasis
osteosarcoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.641187/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.641187/full

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