A Case of ALK-Rearranged Combined Lung Adenocarcinoma and Neuroendocrine Carcinoma with Diffuse Bone Metastasis and Partial Response to Alectinib

A Case of ALK-Rearranged Combined Lung Adenocarcinoma and Neuroendocrine Carcinoma with Diffuse Bone Metastasis and Partial Response to Alectinib

We report a rare case of stage IV pulmonary combined large-cell neuroendocrine carcinoma (LCNEC) and adenocarcinoma (ACA), both demonstrating anaplastic lymphoma kinase (<i>ALK</i>) rearrangement by IHC and FISH. This 61-year-old lifelong nonsmoking Asian woman presented with a cough, an...

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Bibliographic Details
Main Authors: Chloe A. Lim, Norbert Banyi, Tracy Tucker, Diana N. Ionescu, Barbara Melosky
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Current Oncology
Subjects:
neuroendocrine
adenocarcinoma
driver mutation
ALK
LCNEC
Online Access:https://www.mdpi.com/1718-7729/29/2/72

Internet

https://www.mdpi.com/1718-7729/29/2/72

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