Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation
Abstract Background The prevalence of osteoarthritis (OA) is increasing, yet clinically effective and economical treatments are unavailable. We have previously proposed a cell-free fat extract (CEFFE) containing multiple cytokines, which possessed antiapoptotic, anti-oxidative, and proliferation pro...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-04-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-022-02813-3 |