Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation

Cell-free fat extract attenuates osteoarthritis via chondrocytes regeneration and macrophages immunomodulation

Abstract Background The prevalence of osteoarthritis (OA) is increasing, yet clinically effective and economical treatments are unavailable. We have previously proposed a cell-free fat extract (CEFFE) containing multiple cytokines, which possessed antiapoptotic, anti-oxidative, and proliferation pro...

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Bibliographic Details
Main Authors: Zhuoxuan Jia, Bijun Kang, Yizuo Cai, Chingyu Chen, Zheyuan Yu, Wei Li, Wenjie Zhang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Stem Cell Research & Therapy
Subjects:
Osteoarthritis
Cartilage regeneration
Synovitis
Macrophage
Online Access:https://doi.org/10.1186/s13287-022-02813-3

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