Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8.

Previous studies have demonstrated that the cell surface receptor Slamf1 (CD150) is requisite for optimal NADPH-oxidase (Nox2) dependent reactive oxygen species (ROS) production by phagocytes in response to Gram- bacteria. By contrast, Slamf8 (CD353) is a negative regulator of ROS in response to Gra...

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Bibliographic Details
Main Authors: Guoxing Wang, Boaz J van Driel, Gongxian Liao, Michael S O'Keeffe, Peter J Halibozek, Jacky Flipse, Burcu Yigit, Veronica Azcutia, Francis W Luscinskas, Ninghai Wang, Cox Terhorst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4370648?pdf=render