Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS

Abstract Acute respiratory distress syndrome (ARDS) is a common complication of critical illness characterized by lung inflammation, epithelial and endothelial dysfunction, alveolar-capillary leakage, and worsening respiratory failure. The present study aimed to investigate the anti-inflammatory eff...

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Bibliographic Details
Main Authors: Petra Kosutova, Pavol Mikolka, Daniela Mokra, Andrea Calkovska
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Inflammation
Subjects:
Online Access:https://doi.org/10.1186/s12950-023-00337-y