Increased processing of SINE B2 ncRNAs unveils a novel type of transcriptome deregulation in amyloid beta neuropathology

Increased processing of SINE B2 ncRNAs unveils a novel type of transcriptome deregulation in amyloid beta neuropathology

The functional importance of many non-coding RNAs (ncRNAs) generated by repetitive elements and their connection with pathologic processes remains elusive. B2 RNAs, a class of ncRNAs of the B2 family of SINE repeats, mediate through their processing the transcriptional activation of various genes in...

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Bibliographic Details
Main Authors: Yubo Cheng, Luke Saville, Babita Gollen, Christopher Isaac, Abel Belay, Jogender Mehla, Kush Patel, Nehal Thakor, Majid H Mohajerani, Athanasios Zovoilis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
non-coding RNAs
SINE
B2 RNA
hippocampus
transcriptome
amyloid beta pathology
Online Access:https://elifesciences.org/articles/61265

Internet

https://elifesciences.org/articles/61265

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