PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation
The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex.
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14511-w |