PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation

The proteins of the chromosomal passenger complex help chromosomes condense before cell division, but how this complex arrives at chromosomes was not known. Here the authors show that PRMT6 methylates histone H3 to recruit the chromosomal passenger complex.

Bibliographic Details
Main Authors: Seul Kim, Nam Hyun Kim, Ji Eun Park, Jee Won Hwang, Nayeon Myung, Ki-Tae Hwang, Young A Kim, Chang-Young Jang, Yong Kee Kim
Format: Article
Language:English
Published: Nature Portfolio 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14511-w