TLR2/4-mediated NF-κB pathway combined with the histone modification regulates β-defensins and interleukins expression by sodium phenyl butyrate in porcine intestinal epithelial cells

Background: Host defense peptides (HDPs) possess direct antibacterial, antineoplastic, and immunomodulatory abilities, playing a vital role in innate immunity. Dietary-regulated HDP holds immense potential as a novel pathway for preventing infection. Objective: In this study, we examined the regulat...

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Bibliographic Details
Main Authors: Xiujing Dou, Junlan Han, Qiuyuan Ma, Baojing Cheng, Anshan Shan, Nan Gao, Yu Yang
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2018-12-01
Series:Food & Nutrition Research
Subjects:
Online Access:https://foodandnutritionresearch.net/index.php/fnr/article/view/1493/9028