TLR2/4-mediated NF-κB pathway combined with the histone modification regulates β-defensins and interleukins expression by sodium phenyl butyrate in porcine intestinal epithelial cells
Background: Host defense peptides (HDPs) possess direct antibacterial, antineoplastic, and immunomodulatory abilities, playing a vital role in innate immunity. Dietary-regulated HDP holds immense potential as a novel pathway for preventing infection. Objective: In this study, we examined the regulat...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Swedish Nutrition Foundation
2018-12-01
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Series: | Food & Nutrition Research |
Subjects: | |
Online Access: | https://foodandnutritionresearch.net/index.php/fnr/article/view/1493/9028 |