TRIB3‒GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target

TRIB3‒GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target

Pulmonary fibrosis (PF) is a chronic, progressive, fatal interstitial lung disease with limited available therapeutic strategies. We recently reported that the protein kinase glycogen synthase kinase-3β (GSK-3β) interacts with and inactivates the ubiquitin-editing enzyme A20 to suppress the degradat...

Full description

Bibliographic Details
Main Authors: Shanshan Liu, Xiaoxi Lv, Xupeng Wei, Chang Liu, Qiao Li, Jiali Min, Fang Hua, Xiaowei Zhang, Ke Li, Pingping Li, Yang Xiao, Zhuowei Hu, Bing Cui
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Acta Pharmaceutica Sinica B
Subjects:
E3 ligase
Lung injury
Protein phosphorylation
Protein–protein interaction
Ubiquitination
TRIB3
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521002495

Internet

http://www.sciencedirect.com/science/article/pii/S2211383521002495

Similar Items