The GAG-Binding Peptide MIG30 Protects against Liver Ischemia-Reperfusion in Mice

The GAG-Binding Peptide MIG30 Protects against Liver Ischemia-Reperfusion in Mice

Ischemia-reperfusion injury (IRI) drives graft rejection and is the main cause of mortality after liver transplantation. During IRI, an intense inflammatory response marked by chemokine production and neutrophil recruitment occurs. However, few strategies are available to restrain this excessive res...

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Bibliographic Details
Main Authors: Thiago Henrique Caldeira Oliveira, Vincent Vanheule, Sofie Vandendriessche, Fariba Poosti, Mauro Martins Teixeira, Paul Proost, Mieke Gouwy, Pedro Elias Marques
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
liver
ischemia-reperfusion
chemokines
glycosaminoglycans
neutrophils
inflammation
Online Access:https://www.mdpi.com/1422-0067/23/17/9715

Internet

https://www.mdpi.com/1422-0067/23/17/9715

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