Immune cells transcriptome-based drug repositioning for multiple sclerosis

Immune cells transcriptome-based drug repositioning for multiple sclerosis

ObjectiveFinding target genes and target pathways of existing drugs for drug repositioning in multiple sclerosis (MS) based on transcriptomic changes in MS immune cells.Materials and MethodsBased on transcriptome data from Gene Expression Omnibus (GEO) database, differentially expressed genes (DEGs)...

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Bibliographic Details
Main Authors: Xinyue Yin, Xinming Rang, Xiangxiang Hong, Yinglian Zhou, Chaohan Xu, Jin Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
transcriptome
drug repositioning
differentially expressed gene
candidate drug
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020721/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1020721/full

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