The NLRP3 inflammasome recognizes alpha-2 and alpha-7.3 giardins and decreases the pathogenicity of Giardia duodenalis in mice

The NLRP3 inflammasome recognizes alpha-2 and alpha-7.3 giardins and decreases the pathogenicity of Giardia duodenalis in mice

Abstract Background Giardia duodenalis is a parasitic organism that can cause giardiasis, an intestinal infection, particularly prevalent in young children, with clinical symptoms of diarrhea. We previously reported that extracellular G. duodenalis triggers intracellular nucleotide-binding oligomeri...

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Bibliographic Details
Main Authors: Panpan Zhao, Jianhua Li, Xin Li, Jingquan Dong, Xiaocen Wang, Nan Zhang, Shan Li, Min Sun, Xichen Zhang, Zhibang Wang, Min Liang, Ying Li, Lili Cao, Pengtao Gong
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Parasites & Vectors
Subjects:
Giardia duodenalis
Alpha-2 giardin
Alpha-7.3 giardin
NLRP3 inflammasome
Pathogenicity
Online Access:https://doi.org/10.1186/s13071-023-05688-2

Internet

https://doi.org/10.1186/s13071-023-05688-2

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