Cytomegalovirus-Driven Adaption of Natural Killer Cells in NKG2Cnull Human Immunodeficiency Virus-Infected Individuals

Cytomegalovirus-Driven Adaption of Natural Killer Cells in NKG2Cnull Human Immunodeficiency Virus-Infected Individuals

Expansion of natural killer (NK) cells expressing NKG2C occurs following human cytomegalovirus (HCMV) infection and is amplified by human immunodeficiency virus (HIV) co-infection. These NKG2C-expressing NK cells demonstrate enhanced CD16-dependent cytokine production and downregulate Fc&epsilon...

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Bibliographic Details
Main Authors: Emilie M. Comeau, Kayla A. Holder, Neva J. Fudge, Michael D. Grant
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
HCMV
HIV
NKG2C
NKG2Cnull
NKG2A
CD16
CD2
PLZF
FcεRIγ
ADCC
Online Access:http://www.mdpi.com/1999-4915/11/3/239

Internet

http://www.mdpi.com/1999-4915/11/3/239

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