Histopathological characterization of carcinoma breast with BRCA1/2 sequence variation in a Tertiary Care Center in Kerala, South India

Histopathological characterization of carcinoma breast with BRCA1/2 sequence variation in a Tertiary Care Center in Kerala, South India

Background: Hereditary breast cancers constitute around 5%–10% of all breast cancers. The most commonly mutated genes in hereditary breast and ovarian cancer syndrome are the BRCA1 and BRCA2 genes. There has not been any research into the histopathological features of BRCA1/2 mutations in breast can...

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Bibliographic Details
Main Authors: Reeba Mary Issac, Prema Saldanha, Jessy Mangalathu Mathai, Jency Mathews, Rebecca Mathews, Bindu Kumari, Tiju Chacko
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Biomedical and Biotechnology Research Journal
Subjects:
brca1
brca2
histopathology
immunohistochemistry
pathogenic mutation
variant of uncertain significance
Online Access:http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2022;volume=6;issue=1;spage=117;epage=121;aulast=Issac

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http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2022;volume=6;issue=1;spage=117;epage=121;aulast=Issac

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