Evolution-Informed Discovery of the Naphthalenone Biosynthetic Pathway in Fungi

Evolution-Informed Discovery of the Naphthalenone Biosynthetic Pathway in Fungi

ABSTRACT Fungi produce a wide diversity of secondary metabolites with interesting biological activities for the health, industrial, and agricultural sectors. While fungal genomes have revealed an unexpectedly high number of biosynthetic pathways that far exceeds the number of known molecules, access...

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Bibliographic Details
Main Authors: Olga V. Mosunova, Jorge C. Navarro-Muñoz, Diksha Haksar, Jacq van Neer, Jelmer Hoeksma, Jeroen den Hertog, Jérôme Collemare
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mBio
Subjects:
biosynthetic gene clusters
comparative genomics
phylogeny
heterologous expression
Aspergillus parvulus
Aspergillus oryzae
Online Access:https://journals.asm.org/doi/10.1128/mbio.00223-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00223-22

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