Phase separations in oncogenesis, tumor progressions and metastasis: a glance from hallmarks of cancer

Abstract Liquid–liquid phase separation (LLPS) is a novel principle for interpreting precise spatiotemporal coordination in living cells through biomolecular condensate (BMC) formation via dynamic aggregation. LLPS changes individual molecules into membrane-free, droplet-like BMCs with specific func...

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Bibliographic Details
Main Authors: Le-Wei Zheng, Cui-Cui Liu, Ke-Da Yu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-023-01522-5