Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents

Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents

The current work aims to design and synthesis a new series of isatin derivatives and greatly enhances their cytotoxic activity. The derivatives 3-((bromophenyl) imino)-1-(morpholino (pyridine) methyl) indolin-2-one, 2-((oxoindoline) amino) benzoic acid, 3-(thiazolo-imino) indolinone, ethyl-2-((oxoin...

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Bibliographic Details
Main Authors: Ameen Ali Abu-Hashem, Sami A. Al-Hussain
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
thioxo-spiroindoline
isoindolinone
isatin
triazole
thiadiazole
hydrazine
Online Access:https://www.mdpi.com/1420-3049/27/3/835

Internet

https://www.mdpi.com/1420-3049/27/3/835

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