Chimeric antigen receptor T cell structure, its manufacturing, and related toxicities; A comprehensive review

Chimeric antigen receptor T cell structure, its manufacturing, and related toxicities; A comprehensive review

Cancer is the leading cause of death globally after cardiovascular diseases. Conventional therapeutic strategies have had minimal success rate. Recently, immunotherapy, particularly chimeric antigen receptor T cells (CAR T cells), has emerged as the most effective against cancer. A patient’s T lymph...

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Bibliographic Details
Main Authors: Ubaid Ahmad, Zafran Khan, Daniya Ualiyeva, Obed Boadi Amissah, Zohaib Noor, Asaf Khan, Nasib Zaman, Marwa Khan, Ayub Khan, Babar Ali
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Advances in Cancer Biology - Metastasis
Subjects:
Chimeric antigen receptor
CAR T-cell
Cancer
Cytokine release syndrome
Lymphocytes
and Immune effector cell-associated neurotoxicity syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S2667394022000090

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http://www.sciencedirect.com/science/article/pii/S2667394022000090

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