Plasma GFAP in Parkinson’s disease with cognitive impairment and its potential to predict conversion to dementia

Abstract Glial fibrillary acidic protein (GFAP) has been suggested as a biomarker for reactive astrogliosis. We measured the levels of plasma GFAP by Simoa in 60 patients with PD with normal cognition, 63 with mild cognitive impairment (PD-MCI), 24 with dementia (PDD) and 15 healthy controls. A subg...

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Bibliographic Details
Main Authors: Yilin Tang, Linlin Han, Shiyu Li, Tianyu Hu, Zhiheng Xu, Yun Fan, Xiaoniu Liang, Huan Yu, Jianjun Wu, Jian Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00447-7