FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines

FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines

Abstract Dendritic cell (DC)-targeted vaccination is a new mode of antigen delivery that relies on the use of monoclonal antibodies (mAb) to target antigen to specific DC subsets. The neonatal Fc receptor (FcRn) is a non-classical Fc receptor that binds to immunoglobulin G (IgG) in acidified endosom...

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Bibliographic Details
Main Authors: Christophe Macri, Matthew Paxman, Devi Jenika, Xiao Peng Lin, Zahra Elahi, Paul A. Gleeson, Irina Caminschi, Mireille H. Lahoud, Jose A. Villadangos, Justine D. Mintern
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00854-8

Internet

https://doi.org/10.1038/s41541-024-00854-8

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