Chimpanzee adenoviral vector prime-boost regimen elicits potent immune responses against Ebola virus in mice and rhesus macaques

ABSTRACTIn the last few decades, Ebola virus (EBOV) has emerged periodically and infected people in Africa, resulting in an extremely high mortality rate. With no available prophylaxis or cure so far, a highly effective Ebola vaccine is urgently needed. In this study, we developed a novel chimpanzee...

Full description

Bibliographic Details
Main Authors: Xi Yang, Xiang Wang, Yufeng Song, Ping Zhou, Dapeng Li, Chao Zhang, Xia Jin, Zhong Huang, Dongming Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1644968