Rhein Protects Against Severe Acute Pancreatitis In vitro and In vivo by Regulating the JAK2/STAT3 Pathway

Rhein Protects Against Severe Acute Pancreatitis In vitro and In vivo by Regulating the JAK2/STAT3 Pathway

Rhein is widely used in inflammation treatment in China, but its effects on severe acute pancreatitis (SAP) have not been studied closely. This study investigated rhein’s protective effects against SAP using in vitro and in vivo models to determine whether its protective mechanism regulated the Janu...

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Bibliographic Details
Main Authors: Xiaofang Yang, Huan Geng, Lijiao You, Lin Yuan, Jialei Meng, Yuhui Ma, Xuelian Gu, Ming Lei
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
rhein
severe acute pancreatitis
JAK2/STAT3
TNF-α
IL-6
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.778221/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.778221/full

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