Exploring the 2′-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

Exploring the 2′-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

2′-hydroxy-chalcones are naturally occurring compounds with a wide array of bioactivity. In an effort to delineate the structural features that favor antioxidant and lipoxygenase (LOX) inhibitory activity, the design, synthesis, and bioactivity profile of a series of 2′-hydroxy-chalcones bearing div...

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Bibliographic Details
Main Authors: Ioanna Kostopoulou, Andromachi Tzani, Nestor-Ioannis Polyzos, Maria-Anna Karadendrou, Eftichia Kritsi, Eleni Pontiki, Thalia Liargkova, Dimitra Hadjipavlou-Litina, Panagiotis Zoumpoulakis, Anastasia Detsi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
chalcones
aurones
butein
sulfuretin
antioxidant activity
lipoxygenase inhibition
Online Access:https://www.mdpi.com/1420-3049/26/9/2777

Internet

https://www.mdpi.com/1420-3049/26/9/2777

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