MiR-548c-3p through suppressing Tyms and Abcg2 increases the sensitivity of colorectal cancer cells to 5-fluorouracil

MiR-548c-3p through suppressing Tyms and Abcg2 increases the sensitivity of colorectal cancer cells to 5-fluorouracil

Background: Colorectal cancer, is one of most prevalent the cancer in the world. 5-Fluorouracil is a standard chemotherapeutic drug while the acquisition of resistance to 5-Fluorouracil is one of the problems during treatment. In this study, we aimed to find the miRNAs that modulate the expression o...

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Bibliographic Details
Main Authors: Elham Khalili, Ali Afgar, Azam Rajabpour, Seyed Hamid Aghaee-Bakhtiari, Khadijeh Jamialahmadi, Ladan Teimoori-Toolabi
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Colorectal neoplasm
Drug resistance
5-Fluorouracil
TYMS protein
Human
ATP binding cassette transporter
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023089831

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http://www.sciencedirect.com/science/article/pii/S2405844023089831

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