Integration of Transcriptome and MicroRNA Profile Analysis of iMSCs Defines Their Rejuvenated State and Conveys Them into a Novel Resource for Cell Therapy in Osteoarthritis

Although MSCs grant pronounced potential for cell therapies, several factors, such as their heterogeneity restrict their use. To overcome these limitations, iMSCs (MSCs derived from induced pluripotent stem cells (iPSCs) have attracted attention. Here, we analyzed the transcriptome of MSCs, iPSCs an...

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Main Authors: Vasileios Konteles, Ioanna Papathanasiou, Maria Tzetis, Evgenios Goussetis, Varvara Trachana, Evanthia Mourmoura, Charalampos Balis, Konstantinos Malizos, Aspasia Tsezou
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/13/1756