ORFeus: a computational method to detect programmed ribosomal frameshifts and other non-canonical translation events
Abstract Background In canonical protein translation, ribosomes initiate translation at a specific start codon, maintain a single reading frame throughout elongation, and terminate at the first in-frame stop codon. However, ribosomal behavior can deviate at each of these steps, sometimes in a progra...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-12-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-023-05602-8 |