Role of JAK3 in the Pathogenesis of Oxidative Stress-Induced Kidney Fibrosis
The Janus kinase (JAK) tyrosine kinase family and JAK/STAT signal transduction pathway may act in kidney fibrogenesis. JAK3 expression was investigated in in vitro and in vivo models of kidney fibrosis involving oxidative stress. There was a marked down-regulation of JAK3 mRNA in rat kidney tubular...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Codon Publications
2018-05-01
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Series: | Journal of Renal and Hepatic Disorders |
Online Access: | https://jrenhep.com/index.php/jrenhep/article/view/30 |