Glutathione depletion triggers actin cytoskeleton changes via actin-binding proteins

Abstract The importance of glutathione (GSH) in alternative cellular roles to the canonically proposed, were analyzed in a model unable to synthesize GSH. Gene expression analysis shows that the regulation of the actin cytoskeleton pathway is strongly impacted by the absence of GSH. To test this hyp...

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Bibliographic Details
Main Authors: Nahum Zepeta-Flores, Mahara Valverde, Alejandro Lopez-Saavedra, Emilio Rojas
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2018-06-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018005010102&lng=en&tlng=en