Cisplatin Dependent Secretion of Immunomodulatory High Mobility Group Box 1 (HMGB1) Protein from Lung Cancer Cells

Cisplatin Dependent Secretion of Immunomodulatory High Mobility Group Box 1 (HMGB1) Protein from Lung Cancer Cells

High mobility group box 1 (HMGB1) is secreted from activated immune cells, necrotic cells, and certain cancers. Previous studies have reported that different patterns of post-translational modification, particularly acetylation and oxidation, mediate HMGB1 release and confer distinct extracellular H...

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Bibliographic Details
Main Authors: Kevin P. Gillespie, Ross Pirnie, Clementina Mesaros, Ian A. Blair
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomolecules
Subjects:
platinum drugs
acetylation
oxidation
immune response
mass spectrometry
chromatography
Online Access:https://www.mdpi.com/2218-273X/13/9/1335

Internet

https://www.mdpi.com/2218-273X/13/9/1335

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