Sexually dimorphic metabolic effects of a high fat diet on knee osteoarthritis in mice

Sexually dimorphic metabolic effects of a high fat diet on knee osteoarthritis in mice

Abstract Background Women have a higher risk of developing osteoarthritis (OA) than men, including with obesity. To better understand this disparity, we investigated sex differences in metabolic and inflammatory factors associated with OA using a diet-induced mouse model of obesity. We hypothesized...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Timothy M. Griffin, Erika Barboza Prado Lopes, Dominic Cortassa, Albert Batushansky, Matlock A. Jeffries, Dawid Makosa, Anita Jopkiewicz, Padmaja Mehta-D’souza, Ravi K. Komaravolu, Michael T. Kinter
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: BMC 2024-12-01
Цуврал:Biology of Sex Differences
Нөхцлүүд:
Sex differences
Osteoarthritis
Obesity
Metabolic syndrome
High fat diet
Gut microbiome
Онлайн хандалт:https://doi.org/10.1186/s13293-024-00680-6

Интернэт

https://doi.org/10.1186/s13293-024-00680-6

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