Identification of Flavonoids from <i>Scutellaria barbata</i> D. Don as Inhibitors of HIV-1 and Cathepsin L Proteases and Their Structure–Activity Relationships

Identification of Flavonoids from <i>Scutellaria barbata</i> D. Don as Inhibitors of HIV-1 and Cathepsin L Proteases and Their Structure–Activity Relationships

<i>Scutellaria barbata</i> D. Don (<b>SB</b>, Chinese: Ban Zhi Lian), a well-known medicinal plant used in traditional Chinese medicine, is rich in flavonoids. It possesses antitumor, anti-inflammatory, and antiviral activities. In this study, we evaluated the inhibitory acti...

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Bibliographic Details
Main Authors: Ting-Ting Tang, Su-Mei Li, Bo-Wen Pan, Jun-Wei Xiao, Yu-Xin Pang, Shou-Xia Xie, Ying Zhou, Jian Yang, Ying Wei
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
<i>Scutellaria barbata</i> D. Don
flavonoids
HIV-1 protease
cathepsin L protease
structure–activity relationships
Online Access:https://www.mdpi.com/1420-3049/28/11/4476

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https://www.mdpi.com/1420-3049/28/11/4476

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