Enhanced expression of natural cytotoxicity receptors on cytokine-induced memory-like natural killer cells correlates with effector function

Enhanced expression of natural cytotoxicity receptors on cytokine-induced memory-like natural killer cells correlates with effector function

IntroductionNatural killer (NK) cells are a key component of the innate immune system, involved in defending the host against virus-infected cells and tumor immunosurveillance. Under in vitro culture conditions, IL-12/15/18 can induce a memory-like phenotype in NK cells. These cytokine-induced memor...

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Bibliographic Details
Main Authors: Sofía Carreira-Santos, Nelson López-Sejas, Marina González-Sánchez, Eva Sánchez-Hernández, Alejandra Pera, Fakhri Hassouneh, Esther Durán, Rafael Solana, Javier G. Casado, Raquel Tarazona
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
NK cells
memory-like
cytokine-induced memory-like NK cells
NKG2D
natural cytotoxicity receptors
degranulation capacity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1256404/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1256404/full

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