Protocol for quantitative reconstruction of cell lineage using mosaic analysis with double markers in mice

Summary: The generation of diverse cell types during development is fundamental to brain functions. We outline a protocol to quantitatively assess the clonal output of individual neural progenitors using mosaic analysis with double markers (MADM) in mice. We first describe steps to acquire and recon...

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Bibliographic Details
Main Authors: Giselle Cheung, Carmen Streicher, Simon Hippenmeyer
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724003228