Effects of Arachidonic Acid and Its Metabolites on Functional Beta-Cell Mass

Arachidonic acid (AA) is a polyunsaturated 20-carbon fatty acid present in phospholipids in the plasma membrane. The three primary pathways by which AA is metabolized are mediated by cyclooxygenase (COX) enzymes, lipoxygenase (LOX) enzymes, and cytochrome P450 (CYP) enzymes. These three pathways pro...

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Bibliographic Details
Main Authors: Karin J. Bosma, Cecilia E. Kaiser, Michelle E. Kimple, Maureen Gannon
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/4/342