Clinical Development of Colony-Stimulating Factor 1 Receptor (CSF1R) Inhibitors

Macrophage infiltration has been identified as an independent poor prognostic factor for several cancers. Macrophages also orchestrate various tumor-promoting processes. This observation sparked an interest to therapeutically target these plastic innate immune cells. To date, blockade of colony-stim...

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Bibliographic Details
Main Author: Chia-Chi Lin
Format: Article
Language:English
Published: Innovative Healthcare Institute 2021-05-01
Series:Journal of Immunotherapy and Precision Oncology
Subjects:
Online Access:https://jipo.org/doi/pdf/10.36401/JIPO-20-32