E-cadherin, actin, microtubules and FAK dominate different spheroid formation phases and important elements of tissue integrity
Spheroids resemble features of tissues and serve as model systems to study cell–cell and cell–ECM interactions in non-adhesive three-dimensional environments. Although it is generally accepted that mature spheroids resemble tissue properties very well, no studies relate different phases in the spher...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2019-01-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/8/1/bio037051 |