Development and implementation of natural killer cell simultaneous ADCC and direct killing assay

Development and implementation of natural killer cell simultaneous ADCC and direct killing assay

Assays to quantify natural killer (NK) cell killing efficacy have traditionally focused on assessing either direct killing or antibody dependent cell-mediated cytotoxicity (ADCC) independently. Due to the probability that immunotherapeutic interventions affect NK cell-mediated direct killing and NK...

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Bibliographic Details
Main Authors: Maia M.C. Bennett-Boehm, Anna R. Mahr, Sean T. Hartwell, Alexander K. Regan, Isabelle S. Weber, Arriana Blackmon, Cami R. Bisson, Angela N. Truong, Bella A. Circo, Jaden Nienhueser, Donald R. Rogers, Nathan Booher, Nithya Rajagopalan, Jacob W.S. Martens, Paul W. Denton
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Heliyon
Subjects:
NK cell
Killing assay
ADCC
Direct killing
Flow cytometry
Immunophenotype
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402310199X

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http://www.sciencedirect.com/science/article/pii/S240584402310199X

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