The microtubule regulator EFA-6 forms cortical foci dependent on its intrinsically disordered region and interactions with tubulins

Summary: The EFA6 protein family, originally identified as Sec7 guanine nucleotide exchange factors, has also been found to regulate cortical microtubule (MT) dynamics. Here, we find that in the mature C. elegans epidermal epithelium, EFA-6 forms punctate foci in specific regions of the apical corte...

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Bibliographic Details
Main Authors: Anjali Sandhu, Xiaohui Lyu, Xinghaoyun Wan, Xuefeng Meng, Ngang Heok Tang, Gilberto Gonzalez, Ishana N. Syed, Lizhen Chen, Yishi Jin, Andrew D. Chisholm
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724011276