AMPK maintains TCA cycle through sequential phosphorylation of PDHA to promote tumor metastasis

Cancer represents the leading public health problem throughout the world. Globally, about one out of six deaths is related to cancer, which is largely due to the metastatic lesions. However, there are no effective strategies for targeting cancer metastasis. Identification of the key druggable target...

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Bibliographic Details
Main Authors: Zhen Cai, Danni Peng, Hui-Kuan Lin
Format: Article
Language:English
Published: Shared Science Publishers OG 2020-11-01
Series:Cell Stress
Subjects:
Online Access:http://www.cell-stress.com/researcharticles/2020a-cai-cell-stress/