Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.

Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.

Pseudomonas aeruginosa (P.a.) infection accounts for nearly 20% of all cases of hospital acquired pneumonia with mortality rates >30%. P.a. infection induces a robust inflammatory response, which ideally enhances bacterial clearance. Unfortunately, excessive inflammation can also have negative ef...

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Bibliographic Details
Main Authors: Naresh Kumar, Matthew J Pestrak, Qian Wu, Omar Santiagonunez Ahumada, Sheri Dellos-Nolan, Noushin Saljoughian, Rajni Kant Shukla, Cortney F Mitchem, Prabhakara R Nagareddy, Latha P Ganesan, Lafuse P William, Daniel J Wozniak, Murugesan V S Rajaram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011573&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011573&type=printable

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