Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis
Abstract Background Over 120 million mice and rats are used annually in research, conventionally housed in shoebox-sized cages that restrict natural behaviours (e.g. nesting and burrowing). This can reduce physical fitness, impair thermoregulation and reduce welfare (e.g. inducing abnormal stereotyp...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-01-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-021-01184-0 |