Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis

Abstract Background Over 120 million mice and rats are used annually in research, conventionally housed in shoebox-sized cages that restrict natural behaviours (e.g. nesting and burrowing). This can reduce physical fitness, impair thermoregulation and reduce welfare (e.g. inducing abnormal stereotyp...

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Bibliographic Details
Main Authors: Jessica Cait, Alissa Cait, R. Wilder Scott, Charlotte B. Winder, Georgia J. Mason
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-021-01184-0