Systemic inflammation is a determinant of outcomes of CD40 agonist–based therapy in pancreatic cancer patients

Agonistic anti-CD40 monoclonal antibody (mAb) therapy in combination with chemotherapy (chemoimmunotherapy) shows promise for the treatment of pancreatic ductal adenocarcinoma (PDA). To gain insight into immunological mechanisms of response and resistance to chemoimmunotherapy, we analyzed blood sam...

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Detaylı Bibliyografya
Asıl Yazarlar: Max M. Wattenberg, Veronica M. Herrera, Michael A. Giannone, Whitney L. Gladney, Erica L. Carpenter, Gregory L. Beatty
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: American Society for Clinical investigation 2021-03-01
Seri Bilgileri:JCI Insight
Konular:
Online Erişim:https://doi.org/10.1172/jci.insight.145389